Certified Transport Registered Nurse Certification Practice Exam

What type of paralytic is succinylcholine classified as?

1. Non-depolarizing

2. Depolarizing

3. Fast-acting

4. Sustained

The correct answer is: Depolarizing

Succinylcholine is classified as a depolarizing neuromuscular blocker. This classification is based on its mechanism of action, which involves mimicking the neurotransmitter acetylcholine. When succinylcholine binds to the acetylcholine receptors at the neuromuscular junction, it causes an initial depolarization or contraction of the muscle fibers. This is followed by a phase of paralysis, as the continued presence of succinylcholine prevents further stimulation of the muscle. This distinct action mechanism is what differentiates depolarizing agents from non-depolarizing agents, which compete with acetylcholine for binding at the postsynaptic receptor without causing initial depolarization. The fast onset and short duration of action of succinylcholine also contribute to its widespread use in rapid sequence intubation during anesthesia, yet it's primarily characterized as a depolarizing paralytic. This classification is critical for understanding the pharmacodynamics and clinical applications of succinylcholine in various medical settings.